Antiretroviral Drug Interactions and Therapeutic Drug Monitoring (TDM)

Drug-drug interactions are frequently observed in clinical practice and are of particular relevance in the field of antiretroviral therapy. This micro skills course introduces basic pharmacokinetic principles, focusing on those that are important in the management of HIV-positive individuals.

Delivery Mode
Online - Self Paced
Course Duration
30-60 minutes
Course Type
Yes, on completion
Course Code
Content Provider
Royal College of Physicians

What will I learn?

  1. By the end of this session you will be able to:
  2. Describe the basic pharmacokinetic principles of an orally available drug and describe the principles of drug-drug pharmacokinetic interactions
  3. List antiretroviral agents which are prone to gastric absorption interactions
  4. Categorise antiretroviral agents as hepatic enzyme inducers, inhibitors or substrates and describe how this categorisation may help predict drug-drug interactions
  5. List important antiretroviral drug-drug interactions and categorise those which are favourable and those un-favourable
  6. Specifically describe antiretroviral drug interactions with statins, TB drugs, gastric acid modifying agents and how these may be managed
  7. Describe further interactions with antiretroviral therapies and complimentary medicines
  8. List the indication and practicalities of TDM

Course provided in association with


  • This eLearning session is provided by the Content Providers listed above but it does not in any way constitute a qualification or accreditation from them.
  • Certificates provided at the end of each session are issued by Talisium under licence and cannot be used by students to seek membership, fellowship or any other form of recognition by the Content Provider.
  • This micro skills course may contain references to UK laws, regulations, policies and practice guidelines.
  • You should apply the lessons within the context of your local environment.
  • This micro skills course may contain features that are not optimised for mobile devices.